Pre-registration substance use, anxiety and depression systematic review

The following PROSPERO pre-registration was created for a review the factors, including their interactions, that contribute to the onset, maintenance and relapse of substance use, anxiety and depressive disorders. This large review study will use ASReview for the screening of the title and abstracts.

Read more about this study in the PROSPERO pre-registration:


Marlies Brouwer, Reinout Wiers, Sofie van den Brand, Laura Hofstee, Rens van de Schoot, Claudi Bockting. Reviewing factors that contribute to substance use, anxiety and depressive disorders. PROSPERO 2021 CRD42021266297 Available from:


This new study is related to the earlier study by Brouwer et al. 2019 about depression relapse and recurrence. Find more information on the systematic review data used for this study here.


Brouwer, M. E., Williams, A. D., Kennis, M., Fu, Z., Klein, N. S., Cuijpers, P., & Bockting, C. L. (2019). Psychological theories of depressive relapse and recurrence: A systematic review and meta-analysis of prospective studiesClinical psychology review74,

Systematic review data